Researchers at institutions such as Kyoto University in Japan reported that they have greatly improved the efficiency of human induced pluripotent stem cells (iPS cells) grown into muscle cells, and can mimic the pathology of muscular dystrophy in vitro through the use of muscle cells obtained by this method. Helps develop new treatments. Stationery Machine,Modeling Clay Kneader,Round Tin Can Fabricating Machine,Square Tin Box Fabricating Machine gstarstationery , https://www.gseraser.com
iPS cells are a type of cells that have the potential to develop into a variety of tissues and organs. Researchers have converted up to 70% to 90% of iPS cells into skeletal muscle cells by injecting a gene called MyoD1 into iPS cells. The conversion efficiency is only about 40%. Experiments show that the skeletal muscle cells thus cultivated have good functions and can contract after receiving electrical stimulation. The researchers then used this kind of skeletal muscle cell to simulate the pathological features of muscular dystrophy caused by mutations in a gene called DYSF, which shows that the muscle cell membrane is easily broken. Studies have confirmed that, in the skeletal muscle cells cultured in the manner described above, the cell membrane can be repaired if the above gene mutations are corrected.
Researchers believe that this will help develop new methods for treating muscular dystrophy.
New technology helps iPS cells become better into muscle cells